![These highlights do not include all the information needed to use BRIMONIDINE TOPICAL GEL safely and effectively. See full prescribing information for BRIMONIDINE TOPICAL GEL.BRIMONIDINE topical gelInitial U.S. Approval: 1996 These highlights do not include all the information needed to use BRIMONIDINE TOPICAL GEL safely and effectively. See full prescribing information for BRIMONIDINE TOPICAL GEL.BRIMONIDINE topical gelInitial U.S. Approval: 1996](https://dailymed.nlm.nih.gov/dailymed/image.cfm?name=carton-rev06-22.jpg&id=683221)
These highlights do not include all the information needed to use BRIMONIDINE TOPICAL GEL safely and effectively. See full prescribing information for BRIMONIDINE TOPICAL GEL.BRIMONIDINE topical gelInitial U.S. Approval: 1996
![Brimonidine gel 0.33% rapidly improves patient‐reported outcomes by controlling facial erythema of rosacea: a randomized, double‐blind, vehicle‐controlled study - Layton - 2015 - Journal of the European Academy of Dermatology and Venereology - Brimonidine gel 0.33% rapidly improves patient‐reported outcomes by controlling facial erythema of rosacea: a randomized, double‐blind, vehicle‐controlled study - Layton - 2015 - Journal of the European Academy of Dermatology and Venereology -](https://onlinelibrary.wiley.com/cms/asset/e34cc4b0-996a-4c89-8154-7af47ccf2e7f/jdv13305-fig-0005-m.jpg)
Brimonidine gel 0.33% rapidly improves patient‐reported outcomes by controlling facial erythema of rosacea: a randomized, double‐blind, vehicle‐controlled study - Layton - 2015 - Journal of the European Academy of Dermatology and Venereology -
![Before and after results of Brimonidine tartrate treatment for rosacea, a new medicated gel reduces redness and the appearance of blood vessels. Stock Photo | Adobe Stock Before and after results of Brimonidine tartrate treatment for rosacea, a new medicated gel reduces redness and the appearance of blood vessels. Stock Photo | Adobe Stock](https://as2.ftcdn.net/v2/jpg/02/87/65/85/1000_F_287658554_DlRWYmpXsG0aZ8vuZaTR95JWJQKfDT6H.jpg)
Before and after results of Brimonidine tartrate treatment for rosacea, a new medicated gel reduces redness and the appearance of blood vessels. Stock Photo | Adobe Stock
![Paradoxical Erythema Reaction of Long-term Topical Brimonidine Gel for the Treatment of Facial Erythema of Rosacea - JDDonline - Journal of Drugs in Dermatology Paradoxical Erythema Reaction of Long-term Topical Brimonidine Gel for the Treatment of Facial Erythema of Rosacea - JDDonline - Journal of Drugs in Dermatology](http://dl.jddonline.com/articleimages/article_3018/table1.png)